TSD Program Special Projects

Funding Opportunity Number

PCCR-TSD-FY2024-01

Funding Opportunity Title

TSD PROGRAM SPECIAL PROJECTS

Key Dates

Events	Cycle 1
Announcement	January 4, 2024
Due	February 29, 2024
Award Amount	Varies

Administrative Contact

Kim Sagendorf (ksagendorf@purdue.edu)

Funding Opportunity Description: The Targets, Structures and Drugs (TSD) Program of the Purdue Institute for Cancer Research (PCCR) would like to allocate funds to support the following project options:

TSD Collaborative Pilot Grant (up to $10,000)

For projects supporting the TSD drug development pipeline. A collaborative team must be composed of members of either two different Research Clusters in TSD (Target Validation, Chemical and Structural Biology, and Medicinal Chemistry) or of two different Programs in the cancer institute. These grants can provide some trainee support and supplies for projects. Preference is for new collaborations, but new directions for existing collaborations are also acceptable. Preference will be given to projects that could at least in principle generate a submitted extramural grant or publication within a year.

TSD Shared Resource Grant (up to $5,000)

Funds to use cancer institute shared resources to advance cancer related projects relevant to the TSD drug development pipeline or to generate data that would strongly support future grant applications with a cancer focus. Cannot be used to support projects that have already received Shared Resource Funding from the cancer institute.

CLICK HERE to submit your electronic application by 5 pm on the cycle due date. No exceptions. The electronic submission system will not allow applications beyond the deadline. Once here, you can enter your Purdue e-mail and password.

Qualifications/Restrictions: Applicants must be current members of the Purdue University Center for Cancer Research and members of the Targets, Structures and Drugs program.

Cost share: This announcement does not require cost sharing.

Funds Available and Anticipated Number of Awards: The number of awards is contingent upon cancer institute endowments, gifts and other funds and the submission of meritorious applications. For projects involving members of PIIN there may be matching funding available if the project fits with the objectives of the institute.

Award Budget: The proposal will be funded at a level appropriate for the proposed work. See restrictions.

Award Project Period: See the individual descriptions that follow; however, it is expected that work will commence within less than two (2) months of the date of award. A project period of no more than six (6) months will be assigned to projects. If funds are not spent by 10/31/2024, funds will be returned to the Purdue Center for Cancer Research.

Award Restrictions: Restrictions are listed in descriptions above.

Award Requirements: Acceptance of an award will indicate your willingness to serve on the Center’s Pilot Grants Review Committee and to possibly represent the Center at the annual Indiana Elks Convention. The awardee MUST acknowledge the cancer institute. Suggested publication acknowledgement:

“The authors gratefully acknowledge the <insert shared resource name, as appropriate> and support from the Purdue University Institute for Cancer Research, P30CA023168”

No Cost Extension (NCE): No cost extensions are highly discouraged. An exception might be considered on a case-by-case basis. Requests must be made to the administration of the cancer institute and TSD leadership. The institute is very interested in making sure the project is advancing and achieving funding and scholarly production for its NCI renewal.

Regulatory: Please note the award is contingent upon obtaining all of the necessary regulatory approvals (e.g., IRB, IACUC, PACUC) or a Memorandum of Understanding (MOU) pertaining to the work that has pending approvals.

Reporting: Responding to periodic request of progress is required. Triage of future applications may occur if reporting requests are ignored.

Proposal Guidelines:

For TSD Collaborative Pilot Grant:

Proposal Length: The proposal should be single-spaced and a combined maximum of five pages in length (Arial, 11pt) with no less than 0.5-inch margins.
Required Proposal Structure:
1. One (1) page cover letter that indicates which type of grant is being requested and which TSD program members are involved in the proposal.
2. Two (2) page proposal
  1. Proposal Title
  2. Background
  3. Significance
  4. Preliminary data
  5. Research strategy
  6. Brief description of how the project will fit into long term plans to obtain grants, publications, or new therapeutic approaches
    1. If you were awarded prior TSD Special Project funds, provide a one paragraph summary of outcomes from that grant, such as publication or grant submitted based on preliminary data from that grant.
3. One (1) page bibliography
4. One (1) budget justification (budget amounts entered into the online portal)
5. Letters of support from directors of core facilities, CRO's, or external collaborators, as appropriate. Letters do not count toward five (5) page limit.

For TSD Shared Resource Grant:

Proposal Length: The proposal should be single-spaced and a maximum of two pages in length (Arial, 11pt) with no less than 0.5-inch margins.
Required Proposal Structure:
1. Title, Applicant(s) name, Applicant’s program and proposed facility
2. Brief Significance and Background
3. Cancer-relevance: Describe clearly the cancer-relevance of your proposed project in the Background and Significance section.
4. Approach: Please see the facility descriptions for specific information.
5. Timeline and Specific Outcomes: Describe the expected outcomes and evidence that it will be ready to start within two (2) months. The applicant must specify the following:
  1. A peer-reviewed grant submission that will incorporate the data acquired from the shared resource, and/or
  2. Contributions of the shared resource data to a new or re-submission peer-reviewed publication.
  3. The granting agency or journal should be clearly identified as well as the timeline given for the submission. Preference will be given to proposals that have been scored but not funded and are in need of additional supporting data.
  4. If you were awarded prior TSD Special Project funds, provide a one paragraph summary of outcomes from that grant, such as publication or grant submitted based on preliminary data from that grant.
Interaction with the shared resource staff to plan the budget and design of experiments is required.
For the electronic submission, the items to upload should include (all combined into 1 file):
1. Two-page proposal
2. Cited literature (not included in the page limit)
3. NIH Biosketch
4. Current and Pending Funding

Announcement History and Updates

Funding Opportunity Number	Summary of Change
PICR-TSD-FY2024-01	Initiation of Announcement